Chronic Excessive Alcohol Consumption and Male Fertility
Chronic Excessive Alcohol Consumption and Male Fertility
With the exception of a relapse in January 2011 and despite the occurrence of episodes of anxiety, the patient has (as of January 2013) maintained his abstinence from alcohol. The patient's alcohol abstinence was associated with an improvement in the relationship with his partner.
Semen parameters are summarized in Table 1. Azoospermia was evidenced by a semen analysis 2 months after alcohol withdrawal and oligo-asthenoteratospermia was observed 2 months later. Normal semen counts and motility were observed 6 months after alcohol withdrawal. Oligospermia and asthenospermia were respectively found 14 and 22 months after alcohol withdrawal. In the five consecutive sperm analyses, the proportion of sperm with a normal shape ranged from 0 to 2%.
For the first ICSI cycle, a single embryo was placed in the uterus but the resulting pregnancy ended in miscarriage. After the second ICSI cycle, a healthy baby (weighing 4 kg and measuring 52 cm) was born after 40.5 weeks of gestation.
Results
Alcohol Abstinence
With the exception of a relapse in January 2011 and despite the occurrence of episodes of anxiety, the patient has (as of January 2013) maintained his abstinence from alcohol. The patient's alcohol abstinence was associated with an improvement in the relationship with his partner.
Male Fertility Evaluation
Semen parameters are summarized in Table 1. Azoospermia was evidenced by a semen analysis 2 months after alcohol withdrawal and oligo-asthenoteratospermia was observed 2 months later. Normal semen counts and motility were observed 6 months after alcohol withdrawal. Oligospermia and asthenospermia were respectively found 14 and 22 months after alcohol withdrawal. In the five consecutive sperm analyses, the proportion of sperm with a normal shape ranged from 0 to 2%.
Assisted Reproductive Technology
For the first ICSI cycle, a single embryo was placed in the uterus but the resulting pregnancy ended in miscarriage. After the second ICSI cycle, a healthy baby (weighing 4 kg and measuring 52 cm) was born after 40.5 weeks of gestation.
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